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Shingles Prevention

Shingle: (source:

  • If you have ever had Chicken Pox, you can develop Shingles at any time
  • If you have a weakened immune system it is more difficult to be protected from Shingles


Disease Stage: Diagnosed with either a solid tumor malignancy (STM) or hematologic malignancy (HM), any stage
Status: Actively recruiting
Sponsor: Merck & Co., Inc.
Title: A Randomized, Placebo-Controlled, Clinical Trial to Study the Safety and Efficacy of V212 in Adult Patients with Solid Tumor or Hematologic Malignancy
Phase: III
Purpose: The purpose of this study is to test the safety and tolerability of a research study vaccine for the prevention of shingles in patients with solid tumor malignancy or hematologic malignancy; to compare the effectiveness of the research study vaccine in preventing shingles; and to see how well the study vaccine works in patients with weakened immune systems (decreased ability to fight infection), to prevent shingles.


  • >/= 18 yrs and receiving chemotherapy for STM or HM; OR >/= 50 yrs, have HM, not in remission, regardless of treatment status; AND Not receiving Rituximab currently or within the previous 3 mos., or expected to receive it after vaccination
  • Have never received any varicella or shingles vaccines
  • Have not experienced shingles within the last year
  • Deemed eligible by Investigator

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Robert and Carol Weissman Cancer Center 
Clinical Research Program
501 E. Osceola St.
Stuart, FL 34994
772-288-5858, prompt #4

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